A new blood test can detect eight different cancers in early stages

A new blood test can detect eight different cancers in early stages

A new blood test can detect eight different cancers in early stages

Although the test isn't commercially available yet, it will be used to screen 50,000 middle-aged women with no history of cancer as part of a $50 million, five-year study with the Geisinger Health System in Pennsylvania, a spokesperson with the insurer said. CancerSEEK was able to spot cancer 78% of the time in people who had been diagnosed with stage 3 cancer, 73% of the time in people with stage 2 cancer and 43% of the time in people diagnosed with stage 1 cancer. Another issue with liquid biopsies is the ability to identify the underlying tissue of origin. A different Johns Hopkins team managed to identify mutated DNA in a blood sample as a marker of early-stage cancer.

According to the researchers, these cancers cause more than 60 percent of cancer deaths in the US.

The scientists optimized the panel by working to the concept of diminishing returns.

The findings were published in the journal Science. The result was a "small but robust" panel of highly selective DNA markers. "The outcomes are sufficient to warrant the following stage, which is to test this in a screening setting, which means in a large number of people that really don't have growth and see extremely how well our test functions".

Australian researchers on Friday said they have helped develop a new blood test for the early detection of eight common cancers, in a move that could diagnose tumors before they spread and increase patients' chances of survival.

Success rates for individual cancers varied from 98 percent in people with ovarian tumours to 33 percent in people with breast tumours.

Eight hundred volunteers who had not yet been diagnosed with cancer were also tested. Breast cancer is one of the cancers the new blood test can detect.

CancerSEEK, which is the culmination of 30 years of research, uses two signs to determine whether a person might have cancer.

The researchers also wanted to be able to use the test results to predict the site of a tumor.

Professor Gibbs said the blood tests could accurately detect the early stages of cancer well before symptoms were present.

As study co-author Kenneth Kinzler, Ph.D. - co-director of the Ludwig Center for Cancer Genetics and Therapeutics at Johns Hopkins - notes, "Very high specificity was essential because false-positive results can subject patients to unnecessary invasive follow-up tests and procedures to confirm the presence of cancer".

For those who test positive twice, the next step will be imaging to find the tumor. But detecting the scant DNA released by early stage tumors is still challenging. CancerSEEK tests were positive in a median of 70% of the eight cancer types.

Those cancers included ovarian, pancreatic, stomach, liver and esophageal cancers.

The medical holy grail of a blood test for cancer has moved a step closer after a U.S. trial of a new technique detected eight different kinds of tumour. "This has the potential to substantially impact patients".

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